Genetics: Mini-Review of the Molecular Genetics of BRCA1/BRCA2
Goal:

Explain the molecular basis of hereditary breast and ovarian cancer.

: 1 hr

After completing this activity participants will be able to:

  • Describe the size and location of the BRCA genes

  • Discuss the normal function of the BRCA genes

  • Describe how a mutation in BRCA genes results in cancer

  • Locate genetic resources for patients and medical staff


Professional Practice GapsIn an effort to define what healthcare providers need to know about medical genetics, several organizations developed core competencies (NCHPEG, 2000; ASHG, 2001). However, because clinical genetics is a relatively young and evolving field of medicine, many practitioners received insufficient formal genetics education. As a result, they express a lack of confidence in their clinical genetics knowledge and a lack of confidence in their ability to provide genetic counseling. References
Association of Professors of Human and Medical Genetics, American Society of Human Genetics. Medical school core curriculum in genetics. ASHG Website. December 2001. Available at: http://www.ashg.org/pdf/Medical%20School%20Core%20Curriculum%20in%20Genetics.pdf Accessed on: 2004-06-15.
Core competencies in genetics essential for all health-care professionals. National Coalition for Health Professional Education in Genetics. 2000. Available at: http://www.nchpeg.org/ Accessed on: 2004-09-21.